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Author Zuniga, A.; de la Fuente, F.; Federici, F.; Lionne, C.; Bonnet, J.; de Lorenzo, V.; Gonzalez, B. pdf  doi
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  Title An Engineered Device for Indoleacetic Acid Production under Quorum Sensing Signals Enables Cupriavidus pinatubonensis JMP134 To Stimulate Plant Growth Type
  Year 2018 Publication Acs Synthetic Biology Abbreviated Journal ACS Synth. Biol.  
  Volume 7 Issue 6 Pages 1519-1527  
  Keywords Arabidopsis thaliana; Cupriavidus pinatubonensis; quorum sensing; synthetic beneficial interaction  
  Abstract The environmental effects of chemical fertilizers and pesticides have encouraged the quest for new strategies to increase crop productivity with minimal impacts on the natural medium. Plant growth promoting rhizobacteria (PGPR) can contribute to this endeavor by improving fitness through better nutrition acquisition and stress tolerance. Using the neutral (non PGPR) rhizobacterium Cupriavidus pinatubonensis JMP134 as the host, we engineered a regulatory forward loop that triggered the synthesis of the phytohormone indole-3-acetic acid (IAA) in a manner dependent on quorum sensing (QS) signals. Implementation of the device in JMP134 yielded synthesis of IAA in an autoregulated manner, improving the growth of the roots of inoculated Arabidopsis thaliana. These results not only demonstrated the value of the designed genetic module, but also validated C. pinatubonensis JMP134 as a suitable vehicle for agricultural applications, as it is amenable to genetic manipulations.  
  Address [Zuniga, Ana; de la Fuente, Francisco; Gonzalez, Bernardo] Univ Adolfo Ibanez, Fac Ingn & Ciencias, Ctr Appl Ecol & Sustainabil, Santiago 2640, Chile, Email: ana.zuniga@cbs.cnrs.fr  
  Corporate Author Thesis  
  Publisher Amer Chemical Soc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2161-5063 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000435746400005 Approved  
  Call Number UAI @ eduardo.moreno @ Serial 877  
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