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Author (up) Hamant, O.; Inoue, D.; Bouchez, D.; Dumais, J.; Mjolsness, E. doi  openurl
  Title Are microtubules tension sensors? Type Journal Article
  Year 2019 Publication Nature Communications Abbreviated Journal Nat. Commun.  
  Volume 10 Issue Pages 12 pp  
  Abstract Mechanical signals play many roles in cell and developmental biology. Several mechan-otransduction pathways have been uncovered, but the mechanisms identified so far only address the perception of stress intensity. Mechanical stresses are tensorial in nature, and thus provide dual mechanical information: stress magnitude and direction. Here we propose a parsimonious mechanism for the perception of the principal stress direction. In vitro experiments show that microtubules are stabilized under tension. Based on these results, we explore the possibility that such microtubule stabilization operates in vivo, most notably in plant cells where turgor-driven tensile stresses exceed greatly those observed in animal cells.  
  Address [Hamant, Olivier] UCB Lyon 1, Univ Lyon, Lab Reprod & Dev Plantes, ENS Lyon,INRA,CNRS, 46 Allee Italie, F-69364 Lyon 07, France, Email:  
  Corporate Author Thesis  
  Publisher Nature Publishing Group Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2041-1723 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000469320900002 Approved no  
  Call Number UAI @ eduardo.moreno @ Serial 1033  
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