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Author (up) Millan, C.; Vivanco, J.F.; Benjumeda-Wijnhoven, I.M.; Bjelica, S.; Santibanez, J.F. doi  openurl
  Title Mesenchymal Stem Cells and Calcium Phosphate Bioceramics: Implications in Periodontal Bone Regeneration Type
  Year 2018 Publication Cell Biology And Translational Medicine Abbreviated Journal Adv.Exp.Med.Biol.  
  Volume 1107 Issue Pages 91-112  
  Keywords Bioceramics; Bone regeneration; Calcium phosphate; Dental; Mesenchymal stem cells; Tissue engineering  
  Abstract In orthopedic medicine, a feasible reconstruction of bone structures remains one of the main challenges both for healthcare and for improvement of patients' quality of life. There is a growing interest in mesenchymal stem cells (MSCs) medical application, due to their multilineage differentiation potential, and tissue engineering integration to improve bone repair and regeneration. In this review we will describe the main characteristics of MSCs, such as osteogenesis, immunomodulation and antibacterial properties, key parameters to consider during bone repair strategies. Moreover, we describe the properties of calciumphosphate (CaP) bioceramics, which demonstrate to be useful tools in combination with MSCs, due to their biocompatibility, osseointegration and osteoconduction for bone repair and regeneration. Also, we overview the main characteristics of dental cavity MSCs, which are promising candidates, in combination with CaP bioceramics, for bone regeneration and tissue engineering. The understanding of MSCs biology and their interaction with CaP bioceramics and other biomaterials is critical for orthopedic surgical bone replacement, reconstruction and regeneration, which is an integrative and dynamic medical, scientific and bioengineering field of research and biotechnology.  
  Address [Millan, Carola] Univ Adolfo Ibanez, Fac Artes Liberales, Fac Ingn & Ciencias, Vina Del Mar, Chile, Email:  
  Corporate Author Thesis  
  Publisher Springer International Publishing Ag Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0065-2598 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000458010000007 Approved  
  Call Number UAI @ eduardo.moreno @ Serial 979  
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