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Cardenas, C., Guzman, F., Carmona, M., Munoz, C., Nilo, L., Labra, A., et al. (2020). Synthetic Peptides as a Promising Alternative to Control Viral Infections in Atlantic Salmon. Pathogens, 9(8), 600.
Abstract: Viral infections in salmonids represent an ongoing challenge for the aquaculture industry. Two RNA viruses, the infectious pancreatic necrosis virus (IPNV) and the infectious salmon anemia virus (ISAV), have become a latent risk without healing therapies available for either. In this context, antiviral peptides emerge as effective and relatively safe therapeutic molecules. Based on in silico analysis of VP2 protein from IPNV and the RNA-dependent RNA polymerase from ISAV, a set of peptides was designed and were chemically synthesized to block selected key events in their corresponding infectivity processes. The peptides were tested in fish cell lines in vitro, and four were selected for decreasing the viral load: peptide GIM182 for IPNV, and peptides GIM535, GIM538 and GIM539 for ISAV. In vivo tests with the IPNV GIM 182 peptide were carried out using Salmo salar fish, showing a significant decrease of viral load, and proving the safety of the peptide for fish. The results indicate that the use of peptides as antiviral agents in disease control might be a viable alternative to explore in aquaculture.`
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Mosser, M., Pieressa, F., Reutter, JL., Soto, A., Vrgoc, D. (2022). Querying APIs with SPARQL. Inf. Syst., 105, 101650.
Abstract: Although the amount of RDF data has been steadily increasing over the years, the majority of information on the Web is still residing in other formats, and is often not accessible to Semantic Web services. A lot of this data is available through APIs serving JSON documents. In this work we propose a way of extending SPARQL with the option to consume JSON APIs and integrate this information into SPARQL query answers, obtaining a language that combines data from the �traditional� Web to the Semantic Web. Our proposal is based on an extension of the SERVICE operator with the ability to connect to JSON APIs. With the aim of evaluating these queries as efficiently as possible, we show that the main bottleneck is the amount of API requests, and present an algorithm that produces �worst-case optimal� query plans that reduce the number of requests as much as possible. We note that the analysis of this algorithm is by a reduction to an algorithm for evaluating relational queries with access methods with the minimal number of access queries, which is of independent interest. We show the superiority of the worst-case optimal approach in a series of experiments that take existing SPARQL benchmarks, and augment them with the ability to connect to JSON APIs in order to obtain additional information.
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Wu, Y. X., Huang, M. Y., He, C. N., Wang, K. T., Nhung, N. T. H., Lu, S. M., et al. (2022). The Influence of Air Nanobubbles on Controlling the Synthesis of Calcium Carbonate Crystals. Materials, 15(21), 7437.
Abstract: Numerous approaches have been developed to control the crystalline and morphology of calcium carbonate. In this paper, nanobubbles were studied as a novel aid for the structure transition from vaterite to calcite. The vaterite particles turned into calcite (100%) in deionized water containing nanobubbles generated by high-speed shearing after 4 h, in comparison to a mixture of vaterite (33.6%) and calcite (66.3%) by the reaction in the deionized water in the absence of nanobubbles. The nanobubbles can coagulate with calcite based on the potential energy calculated and confirmed by the extended DLVO (Derjaguin-Landau-Verwey-Overbeek) theory. According to the nanobubble bridging capillary force, nanobubbles were identified as the binder in strengthening the coagulation between calcite and vaterite and accelerated the transformation from vaterite to calcite.
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