Abstract: Deterministic Boolean networks are a type of discrete dynamical systems widely used in the modeling of genetic networks. The dynamics of such systems is characterized by the local activation functions and the update schedule, i.e., the order in which the nodes are updated. In this paper, we address the problem of knowing the different dynamics of a Boolean network when the update schedule is changed. We begin by proving that the problem of the existence of a pair of update schedules with different dynamics is NP-complete. However, we show that certain structural properties of the interaction digraph are sufficient for guaranteeing distinct dynamics of a network. In [1] the authors define equivalence classes which have the property that all the update schedules of a given class yield the same dynamics. In order to determine the dynamics associated to a network, we develop an algorithm to efficiently enumerate the above equivalence classes by selecting a representative update schedule for each class with a minimum number of blocks. Finally, we run this algorithm on the well known Arabidopsis thaliana network to determine the full spectrum of its different dynamics. (C) 2013 Elsevier Inc. All rights reserved.

Abstract: This study investigates future changes in daily precipitation extremes and the involved physics over the global land monsoon (GM) region using climate models from the Coupled Model Intercomparison Project Phase 6 (CMIP6). The daily precipitation extreme is identified by the cutoff scale, measuring the extreme tail of the precipitation distribution. Compared to the historical period, multi-model results reveal a continuous increase in precipitation extremes under four scenarios, with a progressively higher fraction of precipitation exceeding the historical cutoff scale when moving into the future. The rise of the cutoff-scale by the end of the century is reduced by 57.8% in the moderate emission scenario relative to the highest scenario, underscoring the social benefit in reducing emissions. The cutoff scale sensitivity, defined by the increasing rates of the cutoff scale over the GM region to the global mean surface temperature increase, is nearly independent of the projected periods and emission scenarios, roughly 8.0% K−1 by averaging all periods and scenarios. To understand the cause of the changes, we applied a physical scaling diagnostic to decompose them into thermodynamic and dynamic contributions. We find that thermodynamics and dynamics have comparable contributions to the intensified precipitation extremes in the GM region. Changes in thermodynamic scaling contribute to a spatially uniform increase pattern, while changes in dynamic scaling dominate the regional differences in the increased precipitation extremes. Furthermore, the large inter-model spread of the projection is primarily attributed to variations of dynamic scaling among models.

Abstract: In this paper we study the family of freezing cellular automata (FCA) in the context of asynchronous updating schemes. A cellular automaton is called freezing if there exists an order of its states, and the transitions are only allowed to go from a lower to a higher state. A cellular automaton is asynchronous if at each time-step only one cell is updated. We define the problem ASYNCUNSTABILITY, which consists in deciding there exists a sequential updating scheme that changes the state of a given cell.
We begin showing that ASYNCUNSTABILITY is in NL for any one-dimensional FCA. Then we focus on the family of life-like freezing CA (LFCA). We study the complexity of ASYNCUNSTABILITY for all LFCA in the triangular and square grids, showing that almost all of them can be solved in NC, except for one rule for which the problem is NP-Complete. (C) 2021 Elsevier Inc. All rights reserved.

Abstract: We study the complexity of signed majority cellular automata on the planar grid. We show that, depending on their symmetry and uniformity, they can simulate different types of logical circuitry under different modes. We use this to establish new bounds on their overall complexity, concretely: the uniform asymmetric and the non-uniform symmetric rules are Turing universal and have a P-complete prediction problem; the non-uniform asymmetric rule is intrinsically universal; no symmetric rule can be intrinsically universal. We also show that the uniform asymmetric rules exhibit cycles of super-polynomial length, whereas symmetric ones are known to have bounded cycle length. (C) 2017 Elsevier Inc. All rights reserved.

Abstract: Human interactions and perceptions about health risk are essential to understand the evolution over the course of a pandemic. We present a Susceptible-Exposed-Asymptomatic-Infectious-Recovered-Susceptible mathematical model with quarantine and social-distance-dependent transmission rates, to study COVID-19 dynamics. Human activities are split across different location settings: home, work, school, and elsewhere. Individuals move from home to the other locations at rates dependent on their epidemiological conditions and maintain a social distancing behavior, which varies with their location. We perform simulations and analyze how distinct social behaviors and restrictive measures affect the dynamic of the disease within a population. The model proposed in this study revealed that the main focus on the transmission of COVID-19 is attributed to the “home” location setting, which is understood as family gatherings including relatives and close friends. Limiting encounters at work, school and other locations will only be effective if COVID-19 restrictions occur simultaneously at all those locations and/or contact tracing or social distancing measures are effectively and strictly implemented, especially at the home setting.

Abstract: Evidence suggests a strong correlation between the prevalence of HSV-2 (genital herpes) and the perseverance of the HIV epidemic. HSV-2 is an incurable viral infection, characterized by periodic reactivation. We construct a model of the co-infection dynamics between the two diseases by incorporating a time-since-infection variable to track the alternating periods of infectiousness of HSV-2. The model considers only heterosexual relationships and distinguishes three population groups: males, general population females, and female sex workers. We calculate the basic reproduction numbers for each disease that provide threshold conditions, which determine whether a disease dies out or becomes endemic in the absence of the other disease. We also derive the invasion reproduction numbers that determine whether or not a disease can invade into a population in which the other disease is endemic. The calculations of the invasion reproduction numbers suggest a new aspect in their interpretation – the class from which the initial disease carrier arises is important for understanding the invasion dynamics and biological interpretation of the expressions of the reproduction numbers. Sensitivity analysis is conducted to examine the role of model parameters in influencing the model outcomes. The results are discussed in the last section.

Abstract: Determining the architecture of multi-planetary systems is one of the cornerstones of understanding planet formation and evolution. Resonant systems are especially important as the fragility of their orbital configuration ensures that no significant scattering or collisional event has taken place since the earliest formation phase when the parent protoplanetary disc was still present. In this context, TOI-178 has been the subject of particular attention since the first TESS observations hinted at the possible presence of a near 2:3:3 resonant chain. Here we report the results of observations from CHEOPS, ESPRESSO, NGTS, and SPECULOOS with the aim of deciphering the peculiar orbital architecture of the system. We show that TOI-178 harbours at least six planets in the super-Earth to mini-Neptune regimes, with radii ranging from
1.152(-0.070)(+0.073)</textual-form>
1.152-0.070+0.073 to
2.87(-0.13)(+0.14)</textual-form> 2.87-0.13+0.14 Earth radii and periods of 1.91, 3.24, 6.56, 9.96, 15.23, and 20.71 days. All planets but the innermost one form a 2:4:6:9:12 chain of Laplace resonances, and the planetary densities show important variations from planet to planet, jumping from
1.02(-0.23)(+0.28)</textual-form> 1.02-0.23+0.28 to
0.177(-0.061)(+0.055)</textual-form> 0.177-0.061+0.055 times the Earth's density between planets c and d. Using Bayesian interior structure retrieval models, we show that the amount of gas in the planets does not vary in a monotonous way, contrary to what one would expect from simple formation and evolution models and unlike other known systems in a chain of Laplace resonances. The brightness of TOI-178 (H = 8.76 mag, J = 9.37 mag, V = 11.95 mag) allows for a precise characterisation of its orbital architecture as well as of the physical nature of the six presently known transiting planets it harbours. The peculiar orbital configuration and the diversity in average density among the planets in the system will enable the study of interior planetary structures and atmospheric evolution, providing important clues on the formation of super-Earths and mini-Neptunes.

Abstract: Soil ecosystem dynamics are influenced by the composition of bacterial communities and environmental conditions. A common approach to study bacterial successional dynamics is to survey the trajectories and patterns that follow bacterial community assemblages; however early successional stages have received little attention. To elucidate how soil type and chemical amendments influence both the trajectories that follow early compositional changes and the architecture of the community bacterial networks in soil bacterial succession, a time series experiment of soil microcosm experiments was performed. Soil bacterial communities were initially perturbed by dilution and subsequently subjected to three amendments: application of the pesticide 2,4-dichlorophenoxyacetic acid, as a pesticide-amended succession; application of cycloheximide, an inhibitor affecting primarily eukaryotic microorganisms, as a eukaryotic-inhibition bacterial succession; or application of sterile water as a non-perturbed control. Terminal restriction fragment length polymorphism (T-RFLP) analysis of the 16S rRNA gene isolated from soil microcosms was used to generate bacterial relative abundance datasets. Bray-Curtis similarity and beta diversity partition-based methods were applied to identify the trajectories that follow changes in bacterial community composition. Results demonstrated that bacterial communities exposed to these three conditions rapidly differentiated from the starting point (less than 12 h), followed different compositional change trajectories depending on the treatment, and quickly converged to a state similar to the initial community (48-72 h). Network inference analysis was applied using a generalized Lotka-Volterra model to provide an overview of bacterial OTU interactions and to follow the changes in bacterial community networks. This analysis revealed that antagonistic interactions increased when eukaryotes were inhibited, whereas cooperative interactions increased under pesticide influence. Moreover, central OTUs from soil bacterial community networks were also persistent OTUs, thus confirming the existence of a core bacterial community and that these same OTUs could plastically interact according to the perturbation type to quickly stabilize bacterial communities undergoing succession.

Abstract: The orbital parameters of warm Jupiters serve as a record of their formation history, providing constraints on formation scenarios for giant planets on close and intermediate orbits. Here, we report the discovery of TIC.237913194b, detected in full-frame images from Sectors 1 and 2 of the Transiting Exoplanet Survey Satellite (TESS), ground-based photometry (Chilean-Hungarian Automated Telescope, Las Cumbres Observatory Global Telescope), and Fiber-fed Extended Range Optical Spectrograph radial velocity time series. We constrain its mass to M-P = 1.942(-0.091)(+0.091) M-J and its radius to R-P = 1.117(-0.047)(+0.054) R-J, implying a bulk density similar to Neptune's. It orbits a G-type star (M-* = 1.026(-0.055)(+0.057) M-circle dot, V = 12.1 mag) with a period of 15.17 days on one of the most eccentric orbits of all known warm giants (e approximate to 0.58). This extreme dynamical state points to a past interaction with an additional, undetected massive companion. A tidal evolution analysis showed a large tidal dissipation timescale, suggesting that the planet is not a progenitor for a hot Jupiter caught during its high-eccentricity migration. TIC.237913194b further represents an attractive opportunity to study the energy deposition and redistribution in the atmosphere of a warm Jupiter with high eccentricity.