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Affolter, C., Kedzierska, J., Vielma, T., Weisse, B., & Aiyangar, A. (2020). Estimating lumbar passive stiffness behaviour from subject-specific finite element models and in vivo 6DOF kinematics. J. Biomech., 102, 11 pp.
Abstract: Passive rotational stiffness of the osseo-ligamentous spine is an important input parameter for estimating in-vivo spinal loading using musculoskeletal models. These data are typically acquired from cadaveric testing. Increasingly, they are also estimated from subject-specific imaging-based finite element (FE) models, which are typically built from CT/MR data obtained in supine position and employ pure rotation kinematics. We explored the sensitivity of FE-based lumbar passive rotational stiffness to two aspects of functional in-vivo kinematics: (a) passive strain changes from supine to upright standing position, and (b) in-vivo coupled translation-rotation kinematics. We developed subject-specific FE models of four subjects' L4L5 segments from supine CT images. Sagittally symmetric flexion was simulated in two ways: (i) pure flexion up to 12 degrees under a 500 N follower load directly from the supine pose. (ii) First, a displacement-based approach was implemented to attain the upright pose, as measured using Dynamic Stereo X-ray (DSX) imaging. We then simulated in-vivo flexion using DSX imaging-derived kinematics. Datasets from weight-bearing motion with three different external weights [(4.5 kg), (9.1 kg), (13.6 kg)] were used. Accounting for supine-upright motion generated compressive pre-loads approximate to 468 N (+/- 188 N) and a “pre-torque” approximate to 2.5 Nm (+/- 2.2 Nm), corresponding to 25% of the reaction moment at 10 degrees flexion (case (i)). Rotational stiffness estimates from DSX-based coupled translation-rotation kinematics were substantially higher compared to pure flexion. Reaction Moments were almost 90% and 60% higher at 5 degrees and 10 degrees of L4L5 flexion, respectively. Within-subject differences in rotational stiffness based on external weight were small, although between-subject variations were large. (C) 2020 Elsevier Ltd. All rights reserved.
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Allende, H., Elias, C., & Torres, S. (2004). Estimation of the option prime: Microsimulation of backward stochastic differential equations. Int. Stat. Rev., 72(1), 107–121.
Abstract: A mathematical statistical model is needed to obtain an option prime and create a hedging strategy. With formulas derived from stochastic differential equations, the primes for US Dollar/Chilean Pesos currency options using a prime calculator are obtained. Furthermore, a backward simulation of the option prime trajectory is used with a numerical method created for backward stochastic differential equations. The use of statistics in finance is highly important in order to develop complex products.
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Altimiras, F., Uszczynska-Ratajczak, B., Camara, F., Vlasova, A., Palumbo, E., Newhouse, S., et al. (2017). Brain Transcriptome Sequencing of a Natural Model of Alzheimer's Disease. Front. Aging Neurosci., 9, 8 pp.
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Alvarez, C., Moreno, G., Valenzuela, F., Rivera, J. I., Ebensperger, F., Reszka, P., et al. (2023). Use of an electric heater as an idealized firebrand to determine ignition delay time of Eucalyptus globulus leaves. Fire Saf. J., 141, 103923.
Abstract: The Idealized-Firebrand Ignition Test (I-FIT) protocol was used to evaluate the piloted ignition delay times of fuel beds composed of leaves of Eucalyptus globulus (Labill.). The amount of fuel layer used for evaluation ranged between the fraction volume (������) of 0.03 to 0.07 which are values expected to be found in forest bed fuels. A theoretical model was developed to describe the heating and ignition of the fuel beds, based on the thermal ignition theory. The model, which was originally developed for pine needle beds, considers the penetration of radiation to the porous matrix. The model is able to accurately predict the ignition delay time for different values of ������, but shows a poorer accuracy for the temperature evolution. This is explained by the large variability observed for the Eucalyptus leaves.
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Anabalon, A., Canfora, F., Giacomini, A., & Oliva, J. (2012). Black holes with primary hair in gauged N=8 supergravity. J. High Energy Phys., (6), 12 pp.
Abstract: In this paper, we analyze the static solutions for the U(1)(4) consistent truncation of the maximally supersymmetric gauged supergravity in four dimensions. Using a new parametrization of the known solutions it is shown that for fixed charges there exist three Possible black hole configurations according to the pattern of symmetry breaking of the (scalars sector of the) Lagrangian. Namely a black hole without scalar fields, a black hole with a primary hair and a black hole with a secondary hair respectively. This is the first, exact, example of a black hole with a primary scalar hair, where both the black hole and the scalar fields are regular on and outside the horizon. The configurations with secondary and primary hair can be interpreted as a spontaneous symmetry breaking of discrete permutation and reflection symmetries of the action. It is shown that there exist a triple point in the thermodynamic phase space where the three solution coexist. The corresponding phase transitions are discussed and the free energies are written explicitly as function of the thermodynamic coordinates in the uncharged case. In the charged case the free energies of the primary hair and the hairless black hole are also given as functions of the thermodynamic coordinates.
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Antico, F. C., De la Varga, I., Esmaeeli, H. S., Nantung, T. E., Zavattieri, P. D., & Weiss, W. J. (2015). Using accelerated pavement testing to examine traffic opening criteria for concrete pavements. Constr. Build. Mater., 96, 86–95.
Abstract: The risk of cracking in a concrete pavement that is opened to traffic at early ages is related to the maximum tensile stress sigma(I), that develops in the pavement and its relationship to the measured, age dependent, flexural strength of a beam,f(r). The stress that develops in the pavement is due to several factors including traffic loading and restrained volume change caused by thermal or hygral variations. The stress that develops is also dependent on the time-dependent mechanical properties, pavement thickness, and subgrade stiffness. There is a strong incentive to open many pavements to traffic as early as possible to allow construction traffic or traffic from the traveling public to use the pavement. However, if the pavement is opened to traffic too early, cracking may occur that may compromise the service life of the pavement. The purpose of this paper is two-fold: (1) to examine the current opening strength requirements for concrete pavements (typically a flexural strength from beams, f(r)) and (2) to propose a criterion based on the time-dependent changes of sigma(I)/f(r), which accounts for pavement thickness and subgrade stiffness without adding unnecessary risk for premature cracking. An accelerated pavement testing (APT) facility was used to test concrete pavements that are opened to traffic at an early age to provide data that can be compared with an analytical model to determine the effective sigma(I)/f(r), based on the relevant features of the concrete pavement, the subgrade, and the traffic load. It is anticipated that this type of opening criteria can help the decision makers in two ways: (1) it can open pavement sections earlier thereby reducing construction time and (2) it may help to minimize the use of materials with overly accelerated strength gain that are suspected to be more susceptible to develop damage at early ages than materials that gain strength more slowly. (C) 2015 Elsevier Ltd. All rights reserved.
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Aquea, F., Timmermann, T., & Herrera-Vasquez, A. (2017). Chemical inhibition of the histone acetyltransferase activity in Arabidopsis thaliana. Biochem. Biophys. Res. Commun., 483(1), 664–668.
Abstract: Chemical inhibition of chromatin regulators provides an effective approach to investigate the roles of chromatin modifications in plant and animals. In this work, chemical inhibition of the Arabidopsis histone acetyltransferase activity by gamma-butyrolactone (MB-3), the inhibitor of the catalytic activity of mammalian GENERAL CONTROL NON-REPRESSIBLE 5 (GCN5) is evaluated. Arabidopsis seedlings were germinated in LS medium supplemented with different concentrations of MB-3, and inhibition in the root length and yellowed leaves were observed. The yellowed leaves phenotype of the plants grown in 100 μM of MB-3 was reverted when plants were additionally treated with 1 μM of TSA, a histone deacetylase inhibitor. Using an immunoblot assay with specific antibodies revealed a reduction of H3K14 acetylation levels at 3 and 24 h post-treatment. At 24 h post-treatment a reduction of H3K9 acetylation levels was observed. Targets of GCN5 related to stress were downregulated at 3 h post-treatment but no change was observed in target genes related to developmental transition. Our results indicate that MB-3 is a chemical inhibitor of the histone acetyltransferase in Arabidopsis and suggest that this inhibitor could function in other plants species. (C) 2016 Elsevier Inc. All rights reserved.
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Aquea, F., Vega, A., Timmermann, T., Poupin, M. J., & Arce-Johnson, P. (2011). Genome-wide analysis of the SET DOMAIN GROUP family in Grapevine. Plant Cell Reports, 30(6), 1087–1097.
Abstract: The SET DOMAIN GROUP (SDG) proteins represent an evolutionarily-conserved family of epigenetic regulators present in eukaryotes and are putative candidates for the catalysis of lysine methylation in histones. Plant genomes analyses of this family have been performed in arabidopsis, maize, and rice and functional studies have shown that SDG genes are involved in the control of plant development. In this work, we describe the identification and structural characterization of SDG genes in the Vitis vinifera genome. This analysis revealed the presence of 33 putative SDG genes that can be grouped into different classes, as it has been previously described for plants. In addition to the SET domain, the proteins identified possessed other domains in the different classes. As part of our study regarding the growth and development of grapevine, we selected eight genes and their expression levels were analyzed in representative vegetative and reproductive organs of this species. The selected genes showed different patterns of expression during inflorescence and fruit development, suggesting that they participate in these processes. Furthermore, we showed that the expression of selected SDGs changes during viral infection, using as a model Grapevine Leafroll Associated Virus 3-infected symptomatic grapevine leaves and fruits. Our results suggest that developmental changes caused by this virus could be the result of alterations in SDG expression.
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Araya, H., Bahamonde, N., Fermin, L., Roa, T., & Torres, S. (2023). ON THE CONSISTENCY OF LEAST SQUARES ESTIMATOR IN MODELS SAMPLED AT RANDOM TIMES DRIVEN BY LONG MEMORY NOISE: THE JITTERED CASE. Stat. Sin., 33(1), 331–351.
Abstract: In numerous applications, data are observed at random times. Our main purpose is to study a model observed at random times that incorporates a longmemory noise process with a fractional Brownian Hurst exponent H. We propose a least squares estimator in a linear regression model with long-memory noise and a random sampling time called “jittered sampling”. Specifically, there is a fixed sampling rate 1/N, contaminated by an additive noise (the jitter) and governed by a probability density function supported in [0, 1/N]. The strong consistency of the estimator is established, with a convergence rate depending on N and the Hurst exponent. A Monte Carlo analysis supports the relevance of the theory and produces additional insights, with several levels of long-range dependence (varying the Hurst index) and two different jitter densities.
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Araya, H., Bahamonde, N., Fermin, L., Roa, T., & Torres, S. (2023). ON THE CONSISTENCY OF THE LEAST SQUARES ESTIMATOR IN MODELS SAMPLED AT RANDOM TIMES DRIVEN BY LONG MEMORY NOISE: THE RENEWAL CASE. Stat. Sin., 33(1), 1–26.
Abstract: In this study, we prove the strong consistency of the least squares estimator in a random sampled linear regression model with long-memory noise and an independent set of random times given by renewal process sampling. Additionally, we illustrate how to work with a random number of observations up to time T = 1. A simulation study is provided to illustrate the behavior of the different terms, as well as the performance of the estimator under various values of the Hurst parameter H.
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Araya-Letelier, G., Parra, P. F., Lopez-Garcia, D., Garcia-Valdes, A., Candia, G., & Lagos, R. (2019). Collapse risk assessment of a Chilean dual wall-frame reinforced concrete office building. Eng. Struct., 183, 770–779.
Abstract: Several code-conforming reinforced concrete buildings were severely damaged during the 2010 moment magnitude (M-w) 8.8 Chile earthquake, raising concerns about their real collapse margin. Although critical updates were introduced into the Chilean design codes after 2010, guidelines for collapse risk assessment of Chilean buildings remain insufficient. This study evaluates the collapse potential of a typical dual system (shear walls and moment frames) office building in Santiago. Collapse fragility functions were obtained through incremental dynamic analyses using a state-of-the-art finite element model of the building. Site-specific seismic hazard curves were developed, which explicitly incorporated epistemic uncertainty, and combined with the collapse fragility functions to estimate the mean annual frequency of collapse (lambda(c)) values and probabilities of collapse in 50-years (P-c(50)). Computed values of lambda(c) and P-c(50) were on the order of 10(-5)-10(-4), and 0.1-0.7%, respectively, consistent with similar studies developed for buildings in the US. The results also showed that the deaggregation of lambda(c) was controlled by small to medium earthquake intensities and that different models of the collapse fragility functions and hazard curves had a non-negligible effect on lambda(c) and P-c(50), and thus, propagation of uncertainty in risk assessment problems must be adequately taken into account.
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Babonneau, F., Barrera, J., & Toledo, J. (2021). Decarbonizing the Chilean Electric Power System: A Prospective Analysis of Alternative Carbon Emissions Policies. Energies, 14(16), 4768.
Abstract: In this paper, we investigate potential pathways for achieving deep reductions in CO2 emissions by 2050 in the Chilean electric power system. We simulate the evolution of the power system using a long-term planning model for policy analysis that identifies investments and operation strategies to meet demand and CO2 emissions reductions at the lowest possible cost. The model considers a simplified representation of the main transmission network and representative days to simulate operations considering the variability of demand and renewable resources at different geographical locations. We perform a scenario analysis assuming different ambitious renewable energy and emission reduction targets by 2050. As observed in other studies, we show that the incremental cost of reducing CO2 emissions without carbon capture or offset alternatives increases significantly as the system approaches zero emissions. Indeed, the carbon tax is multiplied by a factor of 4 to eliminate the last Mt of CO2 emissions, i.e., from 2000 to almost 8500 USD/tCO(2) in 2050. This result highlights the importance of implementing technology-neutral mechanisms that help investors identify the most cost-efficient actions to reduce CO2 emissions. Our analysis shows that Carbon Capture and Storage could permit to divide by more than two the total system cost of a 100% renewable scenario. Furthermore, it also illustrates the importance of implementing economy-wide carbon emissions policies that ensure that the incremental costs to reduce CO2 emissions are roughly similar across different sectors of the economy.
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Balbontin, C., Hensher, D. A., & Beck, M. J. (2022). Advanced modelling of commuter choice model and work from home during COVID-19 restrictions in Australia. Transp. Res. E-Logist. Transp. Rev., 162, 102718.
Abstract: The decision to work from home (WFH) or to commute during COVID-19 is having a major structural impact on individuals' travel, work and lifestyle. There are many possible factors influencing this non-marginal change, some of which are captured by objective variables while others are best represented by a number of underlying latent traits captured by attitudes towards WFH and the use of specific modes of transport for the commute that have a bio-security risk such as public transport (PT). We develop and implement a hybrid choice model to investigate the sources of influence, accounting for the endogenous nature of latent soft variables for workers in metropolitan areas in New South Wales and Queensland. The data was collected between September-October 2020, during a period of no lockdown and relatively minor restrictions on workplaces and public gatherings. The results show that one of the most important attributes defining the WFH loving attitude is the workplace policy towards WFH, with workers that can decide where to work having a higher probability of WFH, followed by those that are being directed to, relative to other workplace policies. The bio-security concern with using shared modes such as public transport is a key driver of WFH and choosing to commute via the safer environment of the private car.
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Barrera, J., & Araya, H. (2023). Modeling Chile Fishing Data Using Environmental Exogenous Variables with GARCH-X Model. J. Iran. Stat. Soc., 21(1), 19–35.
Abstract: Fishing industry has always been an economic motor in many countries around the world, but the fisheries production faces a lot of uncertainty and instability due to the complex factors involved in its operations. In this article, we consider the problem of modeling Chile fishing data using environmental exogenous variables with generalized autoregressive conditional heteroskedasticity (GARCH-X) type models. We carried out this by proposing an ARMA type model for the mean with GARCH-X noise. First, the ARMA, GARCH and GARCH-X models are briefly introduced and the data is described. The exogenous variables are selected from a group of environmental and climatic indicators by correlational analysis. Then, ARMA GARCH and ARMA GARCH-X models with exogenous variables are fitted and compared by information criteria and classical error measures, and stability of its parameters are checked. The statistical tests and comparisons evidenced that a model with inclusion of external variables in mean and variance with the ARMA GARCH-X specification performed better and adjusted the observed values more rigorously. Finally, some conclusions and possible refinations of the applied techniques are given.
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Beltran, J. F., Nunez, E., Nunez, F., Silva, I., Bravo, T., & Moffat, R. (2018). Static response of asymmetrically damaged metallic strands: Experimental and numerical approach. Constr. Build. Mater., 192, 538–554.
Abstract: In this study, the effect of the presence of broken wires (damage) asymmetrically distributed on metallic strands surfaces on their static response is assessed. To this end, a general mechanical model for multi layered strands is presented, in which damaged strands are treated as a 1D nonlinear beam under uncoupled biaxial bending and axial load (NLBM). The NLBM is validated by comparisons with the results obtained from an experimental program especially designed for studying the effect of surface damage distribution on strands response and 3D nonlinear finite element simulations. Analyses are carried out on two strand constructions: 1 x 7 and 1 x 19, in which the damage levels and strand diameters vary from 5% to 40% and from 3.5 mm to 22.2 mm, respectively. Results indicate that the NLBM accurate predicts the static response (residual strength, stiffness, axial strain field, and deformed configuration) of the asymmetrically damaged strands, achieving good computational efficiency and numerical robustness. (C) 2018 Elsevier Ltd. All rights reserved.
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Benavides, C., Diaz, M., O' Ryan, R., Gwinner, S., & Sierra, E. (2021). Methodology to analyse the impact of an emissions trading system in Chile. Clim. Policy, 21(8), 1099–1110.
Abstract: In the context of updating the 2015 Nationally Determined Contribution (NDC), the government of Chile has updated its estimates of compliance costs for a series of mitigation actions with an emphasis on the energy sector as the main source of its greenhouse gas emissions. Using the information developed in this process, we assess the impact on compliance costs of increasing the flexibility for sources by introducing different emissions trading schemes. For this we develop a detailed optimization model that represents the operational and investment decisions that could be taken by the energy generation, industrial and mining sectors if an Emissions Trading System (ETS) was implemented. An ETS with two cap and trade options is analysed together with an offset mechanism for sources not included in the ETS. Also, two policy goals are considered: a stringent 76% sectoral reduction goal in 2050 similar to Chile's current strict NDC, and a more lax 46% goal similar to Chile's initial 2015 NDC proposal. The results show that (i) cost reductions from increased flexibility for Chile's current strict NDC are significant, and that offsets can play an important role; (ii) the stringency of the reduction goal affects the magnitude of the cost savings related to flexibility and, surprisingly, total abatement costs are negative (i.e. there are benefits) for the 46% reduction goal. In this latter case, the most significant cost reductions result from compelling firms to comply with their allowances in each sector, not increased flexibility. These results highlight the policy relevance of case by case analysis using a modelling approach similar to the one we develop here. Key policy insights ETS implementation can help Chile meet its mitigation commitment for 2050. The compliance costs can vary significantly depending on the flexibility implemented in the emissions trading schemes. Optimization models can help decision-makers define the attributes of an ETS, such as the sectors that should participate, the cap, and the percentage of offsets. The proposed methodology also highlights and quantifies the offsets that can be acquired from sectors that are not part of an ETS, such as forestry, agriculture, and the waste sector. The possibility to acquire of offsets could reduce significantly the cost for industries that participate of an ETS.
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Berkovits, N., & Chandia, O. (2014). Simplified pure spinor b ghost in a curved heterotic superstring background. J. High Energy Phys., (6), 12 pp.
Abstract: Using the RNS-like fermionic vector variables introduced in arXiv:1305.0693, the pure spinor b ghost in a curved heterotic superstring background is easily constructed. This construction simplifies and completes the b ghost construction in a curved background of arXiv:1311.7012.
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Bevilacqua, M., Camano-Carrillo, C., & Porcu, E. (2022). Unifying compactly supported and Matern covariance functions in spatial statistics. J. Multivar. Anal., 189, 104949.
Abstract: The Matern family of covariance functions has played a central role in spatial statistics for decades, being a flexible parametric class with one parameter determining the smoothness of the paths of the underlying spatial field. This paper proposes a family of spatial covariance functions, which stems from a reparameterization of the generalized Wendland family. As for the Matern case, the proposed family allows for a continuous parameterization of the smoothness of the underlying Gaussian random field, being additionally compactly supported.
More importantly, we show that the proposed covariance family generalizes the Matern model which is attained as a special limit case. This implies that the (reparametrized) Generalized Wendland model is more flexible than the Matern model with an extra-parameter that allows for switching from compactly to globally supported covariance functions.
Our numerical experiments elucidate the speed of convergence of the proposed model to the Matern model. We also inspect the asymptotic distribution of the maximum likelihood method when estimating the parameters of the proposed covariance models under both increasing and fixed domain asymptotics. The effectiveness of our proposal is illustrated by analyzing a georeferenced dataset of mean temperatures over a region of French, and performing a re-analysis of a large spatial point referenced dataset of yearly total precipitation anomalies.
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Brahm, R., Ulmer-Moll, S., Hobson, M. J., Jordan, A., Henning, T., Trifonov, T., et al. (2023). Three Long-period Transiting Giant Planets from TESS. Astron. J., 165(6), 227.
Abstract: We report the discovery and orbital characterization of three new transiting warm giant planets. These systems were initially identified as presenting single-transit events in the light curves generated from the full-frame images of the Transiting Exoplanet Survey Satellite. Follow-up radial velocity measurements and additional light curves were used to determine the orbital periods and confirm the planetary nature of the candidates. The planets orbit slightly metal-rich late F- and early G-type stars. We find that TOI 4406b has a mass of M ( P ) = 0.30 +/- 0.04 M (J), a radius of R ( P ) = 1.00 +/- 0.02 R (J), and a low-eccentricity orbit (e = 0.15 +/- 0.05) with a period of P = 30.08364 +/- 0.00005 days. TOI 2338b has a mass of M ( P ) = 5.98 +/- 0.20 M (J), a radius of R ( P ) = 1.00 +/- 0.01 R (J), and a highly eccentric orbit (e = 0.676 +/- 0.002) with a period of P = 22.65398 +/- 0.00002 days. Finally, TOI 2589b has a mass of M ( P ) = 3.50 +/- 0.10 M (J), a radius of R ( P ) = 1.08 +/- 0.03 R (J), and an eccentric orbit (e = 0.522 +/- 0.006) with a period of P = 61.6277 +/- 0.0002 days. TOI 4406b and TOI 2338b are enriched in metals compared to their host stars, while the structure of TOI 2589b is consistent with having similar metal enrichment to its host star.
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Caceres, C., Moffat, R., & Pakalnis, R. (2017). Evaluation of flexural failure of sill mats using classical beam theory and numerical models. Int. J. Rock Mech. Min. Sci., 99, 21–27.
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